Overview

Antibiotic Therapy of Acute Uncomplicated Colonic Diverticulitis

Status:
Completed
Trial end date:
2010-12-01
Target enrollment:
0
Participant gender:
All
Summary
The purpose of this study is to evaluate if antibiotic therapy is necessary for treatment of uncomplicated colonic diverticulitis. The hypothesis is that Patients with acute uncomplicated colonic diverticulitis will recover the condition without antibiotic therapy and the lack of antibiotic therapy will not lead to complications. The patients will be randomized to conservative treatment with and without antibiotic therapy.
Phase:
N/A
Accepts Healthy Volunteers?
No
Details
Lead Sponsor:
Uppsala University
Collaborator:
Landstinget i Värmland
Treatments:
Anti-Bacterial Agents
Antibiotics, Antitubercular
Criteria
Inclusion Criteria:

- adults with CT sign of acute colonic uncomplicated diverticulitis

- elevated CRP and LPK

- Temp.38c or more

Exclusion Criteria:

- patients with peritonitis, sepsis or CT- sign of complicated diverticulitis with
abscesses or free abdominal air

- pregnancy

- immunological incompetence and immunosuppressive therapy