Antibiotics Usage in Pediatric Orthopaedic Percutaneous Surgery (APOPS)

• Status: Recruiting
• Trial end date: 2025-12-01
• Target enrollment: 0
• Participant gender: All

Summary

The aim of this study is to determine if antibiotics affect the outcome after percutaneous surgery for pediatric supracondylar humerus fractures. The patient population will be recruited from the cohort presenting to Women and Children's Hospital for percutaneous fixation of pediatric supracondylar humerus fractures who meet the eligibility criteria and consent to taking part in the study. Patients will be followed up for 3-6 weeks depending on age, and will be evaluated on the presence or absence superficial or deep infection, VAS pain scores, time to healing, need for repeat casting, and loss of fixation.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Sumit Gupta
• Collaborator: University of Missouri-Columbia
• Treatments: Anti-Bacterial Agents; Antibiotics, Antitubercular; Cefazolin; Clindamycin; Clindamycin palmitate; Clindamycin phosphate

Criteria

Inclusion Criteria:

• Age<14 years

• Open growth plates

• Gartland type II or III extension type fracture of the distal humerus OR Flexion type fracture of the distal humerus

Exclusion Criteria:

• Need for open reduction

• Need for antibiotics due to other injuries or conditions during the entire study period

• Immunosuppression

• History of malignancy or metabolic bone disease

• Open fractures

• Pre-existing Infection

• Intra-operative breech of sterile technique