Antibiotics Versus Placebo in the Treatment of Abscesses in the Emergency Department

• Status: Terminated
• Trial end date: 2012-10-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to determine if there is a difference between an antibiotic, trimethoprim-sulfamethoxazole versus placebo in healing outcomes of soft tissue abscesses following incision and drainage.

• Phase: N/A
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Children's Mercy Hospital Kansas City
• Collaborator: Blue Cross Blue Shield
• Treatments: Anti-Bacterial Agents; Sulfamethoxazole; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination

Criteria

Inclusion Criteria:

• Age 3 months to 17 years

• Single, localized soft tissue abscesses requiring incision and drainage with purulent material obtained

• Diameter of the abscess less than 5cm as measured by the treating physician

Exclusion Criteria:

• Signs of systemic illness or ill-appearing, as determined by the treating physician

• Admission to the hospital following treatment in the Emergency Department

• Known sulfa allergy

• Immunocompromised patients

• Soft tissue abscesses involving the perineum (labia, scrotum, penis, perirectal)

• Previous antibiotic use (for any reason) in the past seven days

• Non-English speaking patients and families