Endoscopic retrograde cholangiopancreatography (ERCP) is an endoscopic procedure used to
treat bile duct stones, obstructive jaundice, biliary leaks, and a variety of other
conditions.
There is active debate whether antibiotics should be given prophylactically for ERCP outside
of high risk indications including primary sclerosing cholangitis. In part this is due to a
lack of appropriately powered clinical trials with adequate follow up. The aim will be to
assess whether prophylactic antibiotics decrease the rate of post ERCP cholangitis as defined
by the Revised Tokyo Criterion.