Antibiotyping and Prevalence of Virulent Genotypes Among Helicobacter Pylori and Their Impact on Response to Therapy

• Status: Not yet recruiting
• Trial end date: 2023-10-01
• Target enrollment: 0
• Participant gender: All

Summary

• Detection of primary antimicrobial susceptibility and resistance of Helicobacter Pylori infection.

• Detection of resistance and virulence genes of Helicobacter Pylori infection.

• Assessment of H pylori carcinogenicity gene.

• Evaluation of outcome and efficacy of antibiotics regimen will be used in our research.

• Evaluation of effect of other factors as diet (fatty and spicy meal), drugs as NSAIDs use, antibiotics for any cause on response of H pylori to antibiotics regimen.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Assiut University

Criteria

Inclusion Criteria:

• Any patient is above 18 years old with symptomatic H pylori infection patients diagnosed by positive H pylori Ag in stool (naïve treatment).

Exclusion Criteria:

• Patients who aren't eligible to endoscopy.

• Patients are under 18 years old

• Patient's refusal

• history of antibiotics or proton pump inhibitor use during last month.