Anticholinergic Premedication for Sedation With Dexmedetomidine During Spinal Anesthesia
Status:
Completed
Trial end date:
2016-01-01
Target enrollment:
Participant gender:
Summary
Dexmedetomidine is a selective α2 adrenergic receptor antagonist, which has little effect on
respiratory suppression used as sedative agent. Also, dexmedetomidine has been reported to
prolong the anesthesia time when used with patients undergoing spinal anesthesia. However,
dexmedetomidine has sympathetic effect which can cause hypotension and bradycardia dose
dependently. Therefore, this study is aimed to evaluate the effectiveness of premedication of
anticholinergic agents on vital sign in patients undergoing spinal anesthesia.