Antiemetic Efficacy of Ondansetron Versus Metoclopramide

• Status: Unknown status
• Trial end date: 2016-11-01
• Target enrollment: 0
• Participant gender: All

Summary

Acute gastroenteritis (GEA) is a public health problem at present, the main cause of vomiting and consultation in emergencies in children under 5 years. Worldwide, there are about 2 million deaths per year due to gastroenteritis in children under 5 years.

In Mexico, the mortality rate by age in 2013, recorded 28 deaths per 100,000 boys and girls, in 2013 in our country 2.5 million children between 5 and 17 years engaged in an economic activity. The occupancy rate for the child population was 8.6: 11.4 for boys and 5.8 for girls.

NICE guidance gastroenteritis defined as a transient disorder caused by an enteric infection and characterized by a sudden onset of diarrhea with or without vomiting

• Phase: Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Hospital General Naval de Alta Especialidad - Escuela Medico Naval
• Treatments: Antiemetics; Metoclopramide; Ondansetron

Criteria

Inclusion Criteria:

• Orally intolerance

• More than 2 vomiting in the last 24 hours

• Without antiemetic therapy within 24 hours of the clinical picture

• Patients with or without diarrhea

Exclusion Criteria:

• Previous abdominal surgery

• Suspected surgical abdominal

• Vomiting bile

• Hypersensitivity to Ondansetron and Metoclopramide