Antihypertensive Efficacy and Safety of Approved Drugs in Japanese Patients With Essential Hypertension (Banyu Study)(0954A-302)

• Status: Completed
• Trial end date: 2002-11-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to evaluate antihypertensive (lowering blood pressure) effectiveness of three combinations of approved study drugs compared to both study drugs being given alone.

• Phase: Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Merck Sharp & Dohme Corp.
• Treatments: Hydrochlorothiazide; Losartan

Criteria

Inclusion Criteria:

• Japanese ancestry

• Stable high blood pressure defined by the study criteria

Exclusion Criteria:

• Pregnant or nursing

• Significant concurrent kidney, liver, blood, or other disease

• Recent heart attack or heart surgery

• History of stroke, severe hypertension (high blood pressure), significant heart failure or cardiac arrhythmias

• Significant lab abnormalities

• Uncontrolled blood sugar

• History of certain drug allergies