Antimicrobial Efficacy of Biogenic Gold Nano Particle From Pelargonium Graveolens Leaves Extract Mouthwash for Children

• Status: Recruiting
• Trial end date: 2024-03-20
• Target enrollment: 0
• Participant gender: Male

Summary

The study is randomized controlled trial ... The null hypothesis of the present study is that there is no antibacterial efficacy of gold nanoparticles of pelargonium graveolens mouthwash against Streptococcus mutans and Candida Albicans . Meanwhile the alternative hypothesis of the present study is that gold nanoparticles of pelargonium graveolens mouthwash have antimicrobial activity against Streptococcus mutans and Candida Albicans .

• Phase: N/A
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Ahmed Yousif Mahdi
• Collaborator: University of Baghdad
• Treatments: Chlorhexidine; Chlorhexidine gluconate

Criteria

Inclusion Criteria:

• The study sample will include a group if children aged (7-14) years, with mild to moderate crowding, attending the specialist dental center in Diyala city.

• Patients with mild to moderate gingivitis as a base line (for standardization).

• Healthy child without any oral ulceration or systemic medical condition.

• Cooperative child.

• Patient did not take any antibiotics or anti-fungal for at least 4 weeks prior to sampling procedure.

• Children are healthy without any systemic disease .

• From the same geographical area ( Diyala Governorate ).

Exclusion Criteria:

• Children outside specified age.

• Children with systemic disease or on medication.

• Children on a daily fluoride or other therapeutic regimen were excluded from the study.

• Children 's parents who are smokers (passive smoking ) to reduce the confounding factors.

• No more than one child per family to be allowed into the study.

• Children who their parents refuse to participate in the study.