In the last decade, the prevalence of malaria has been escalating at an alarming rate,
especially in Africa. An estimated 300 to 500 million cases each year cause 1.5 to 2.7
million deaths, more than 90% occur in children under 5 years of age in Africa (WHO 1995).
Malaria is Africa's leading cause of under-five mortality (20%) and constitutes 10% of the
continent's overall disease burden. It accounts for 40% of public health expenditure, 30-50%
of inpatient admissions, and up to 50% of outpatient visits in areas with high malaria
transmission. Antioxidant micronutrients have immunomodulatory role and may have suppressive
activity.
Phase:
Phase 3
Details
Lead Sponsor:
University of Lagos, Nigeria
Treatments:
alpha-Tocopherol Amodiaquine Amodiaquine, artesunate drug combination Antioxidants Artemether Artemisinins Artesunate Lumefantrine Micronutrients Retinol palmitate Selenium Tocopherols Tocotrienols Trace Elements Vitamin A Vitamin E Vitamins Zinc