Antioxidant Supplementation in Pregnant Women With Low Antioxidant Status

• Status: Completed
• Trial end date: 2010-02-01
• Target enrollment: 0
• Participant gender: Female

Summary

The purpose of this study is to investigate antioxidants supplementation in pregnant women with low antioxidant status at 10-12 weeks gestation age in relation to adverse pregnancy outcome in randomized prospective study.

• Phase: Phase 2
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Showa University
• Collaborator: Indonesia University
• Treatments: Antioxidants; Ascorbic Acid; Vitamins

Criteria

Inclusion Criteria:

• Agree to consent form, and consent to protocol of research

• Known healthy singleton 6-10 weeks pregnant women

Exclusion Criteria:

• Blood pressure > 135/85

• Proteinuria

• History or current use of anti-hypertensive medication or diuretics

• Use of vitamins C > 150 mg and/or E > 75 IU per day

• Pregestational diabetes

• Known placental abnormalities.

• Current pregnancy is a result of in vitro fertilization

• Regular use of platelet active drugs or non-steroidal anti-inflammatory drugs

• Known fetal abnormalities

• Documented uterine bleeding within a week of screening

• Uterine malformations

• History of medical complications

• Illicit drug or alcohol abuse during current pregnancy

• Intent to deliver elsewhere

• Known psychologic problems.

• Participating in another interventional study