Antiperistaltic Effect and Safety of Glycopyrronium for Colonoscopic Polypectomy

• Status: Enrolling by invitation
• Trial end date: 2024-06-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to determine the antiperistaltic effect and safety of glycopyrrolate and whether the use of glycopyrrolate is beneficial for colonoscopy and colonoscopic polypectomy.

• Phase: Phase 1/Phase 2
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Jie Chen
• Treatments: Glycopyrrolate

Criteria

Inclusion Criteria:

• Age 18-80 years old.

• Outpatients and inpatients with lesions to be resected under colonoscopy.

• Participants voluntarily participated and signed informed consent forms.

Exclusion Criteria:

• Pregnancy status and lactating women.

• With glaucoma, myasthenia gravis, hyperthyroidism, chronic renal insufficiency, and inflammatory bowel disease.

• With obstructive gastrointestinal diseases such as pyloric obstruction, paralytic ileus, and achalasia of the cardia.

• With obstructive urinary tract diseases such as prostatic hyperplasia and dysuria.

• With heart disease such as arrhythmia (bradycardia, tachycardia, ventricular fibrillation, atrial fibrillation, etc.), coronary heart disease, congestive heart failure.

• With a history of previous abdominal or intestinal surgery.

• Anticholinergic drugs were administered 48 hours before surgery.