Antiretroviral Therapy Adherence and Secondary Prevention of Human Immunodeficiency Virus
Status:
Recruiting
Trial end date:
0000-00-00
Target enrollment:
Participant gender:
Summary
In this study, investigators propose to randomize 165 human immunodeficiency virus positive
patients to one of three 16-week treatment conditions: (1) standard care; (2) standard care
+ cell phone-based adherence reminders; or (3) standard care + cell phone-based adherence
reminders and contingency management. In this latter condition, patients will earn
reinforcement for sending in time- and date-stamped self videos of antiretroviral therapy
medication ingestion. Primary outcomes will include viral loads and self-report measures of
adherence, and effects will be evaluated both during the treatment period and throughout a
one-year follow-up. Investigators hypothesize that the cell phone reminder condition will
improve adherence relative to standard care, and the cell phone reminder plus contingency
management condition will have the best outcomes. Results from this study may have
widespread implications for the use of cell phones as a novel technology to improve initial
adherence to antiretroviral therapy, thereby reducing the spread of drug resistant human
immunodeficiency virus strains to the community.
Phase:
N/A
Details
Lead Sponsor:
UConn Health
Collaborator:
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)