Antiseptic Effects on the Dental Implant Internal Surface Microbiome
Status:
Not yet recruiting
Trial end date:
2023-04-01
Target enrollment:
Participant gender:
Summary
Soldiers operate in environments that are more likely to lead to oral trauma, risking poor
dentition which can directly impact military readiness. Dental restoration can often be
accomplished via dental implant insertion. Microbiome-associated complications that result in
bone loss, including the micro-leakage of bacterial species proliferating in the dental
implant internal cavity, frequently lead to implant failure. Reduction in implant bacterial
load may result in a shift of the composition of the microbiome in favor of less pathogenic
species, potentially improving dental implant success rates, reducing surgical revisions, and
associated cost savings. This study aims to determine how disinfectant gel (hydrogen peroxide
or chlorhexidine) insertion into dental implant internal cavities affects implant failure
rates, bacterial load and microbiome composition.