Apitox, Honeybee Venom Treatment for Osteoarthritis Pain and Inflammation

• Status: Completed
• Trial end date: 2010-04-01
• Target enrollment: 0
• Participant gender: All

Summary

The study will evaluate Apitox, pure honeybee venom as a treatment for pain and inflammation of osteoarthritis of the knee.

• Phase: Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Apimeds, Inc.
• Treatments: Histamine; Histamine phosphate

Criteria

Inclusion Criteria:

• osteoarthritis of one or both knees

• on stable NSAID or none due to intolerance

• women either post menopausal or on stable birth control

• no clinically significant disease or or abnormal laboratory values

• signed informed consent, communicate effectively, understand and comply with all study requirements

Exclusion Criteria:

• serious or unstable medical or psychological condition

• known sensitivity to honeybee venom, histamine or lidocaine

• history of asthma

• any clinically significant ECG abnormalities

• any clinically significant laboratory values OOR

• history of drug or alcohol abuse

• history of joint injury and forms of inflammatory arthritis