Application of Sodium Bicarbonate Ringer's Solution in Laparoscopic Hepatectomy

• Status: Recruiting
• Trial end date: 2023-09-30
• Target enrollment: 0
• Participant gender: All

Summary

Compared the effects of Sodium bicarbonate Ringer's solution and lactate Ringer's solution on the internal environment and hemodynamics of patients during laparoscopic liver resection, to observe the application prospect of sodium bicarbonate Ringer's solution in Laparoscopic hepatectomy.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: The First Affiliated Hospital with Nanjing Medical University
• Treatments: Pharmaceutical Solutions

Criteria

Inclusion Criteria:

1. ≥18 years old,

2. patients who plan to undergoing laparoscopic hepatectomy ;

3. Willing to sign informed consent.

Exclusion Criteria:

1. age <18 years

2. pregnancy

3. active cardiac conditions (unstable coronary syndromes, decompensated heart failure, significant arrhythmias, severe valvular disease, history of congestive heart failure)

4. history of significant cerebrovascular disease

5. restrictive or obstructive pulmonary disease

6. uncontrolled hypertension

7. renal dysfunction (glomerular filtration rate <60 mL/min),

8. evidence of hepatic metabolic disorder (bilirubin >35 mmol/L)

9. presence of active infection