Appropriate Compatibility of Propofol and Sevoflurane for Orthopaedic Surgery of Patients With MCI

• Status: Unknown status
• Trial end date: 2018-11-01
• Target enrollment: 0
• Participant gender: All

Summary

According to the inclusion and exclusion criteria, elderly patients undergoing elective orthopedic surgery were randomly divided into four groups. The different combinations of propofol and sevoflurane were used in the four groups: 1 day before surgery, after patients become wide-awake, and 3 days, 7 days, and 3 months after surgery, the patient's cognitive function was evaluated using a professional cognitive scale and other indicators. Finally, statistical analysis.

• Phase: N/A
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: The Third Central Clinical College of Tianjin Medical University
• Treatments: Propofol; Sevoflurane

Criteria

Inclusion Criteria:

• Elective orthopaedic surgery

• American Society of Anesthesiologists physical status: II

Exclusion Criteria:

• Neurological diseases that may affect cognitive function (e.g., subdural hematoma)

• Hypothyroidism

• Alcoholic dementia