Aqueous Humor Dynamics of NCX 470 Ophthalmic Solution

• Status: Recruiting
• Trial end date: 2025-03-31
• Target enrollment: 0
• Participant gender: All

Summary

This is a double-masked, placebo-controlled study which will determine the action of NCX 470 ophthalmic solution, 0.1% on aqueous humor dynamic parameters in healthy volunteers or subjects with OHT.

• Phase: Phase 2/Phase 3
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Nicox Ophthalmics, Inc.
• Treatments: Bimatoprost; Lubricant Eye Drops; Nitric Oxide

Criteria

Inclusion Criteria:

1. ≥18 years of age

2. Either gender

3. Subjects without glaucoma

4. Qualifying IOP at Screening Visit

Exclusion Criteria:

1. Narrow anterior chamber angles or disqualifying central corneal thickness in either eye

2. Clinically significant ocular disease in either eye

3. Uncontrolled systemic disease

4. Serious hypersensitivity to topical anesthetic eye drops

5. Subjects with a known hypersensitivity or contraindications to any of the ingredients in the study medications