Argatroban Combined With Antiplatelet Versus Antiplatelet for Acute Ischemic Stroke
Status:
Completed
Trial end date:
2019-01-08
Target enrollment:
Participant gender:
Summary
Intravenous thrombolysis is considered as the first choice for ischemic stroke. In the recent
years, endovascular therapy is demonstrated to be effective to treat ischemic with big vessel
occlusion. However, only a minority of patients can get intravenous thrombolysis or
endovascular therapy due to the restricted time window and strict indications. Dual
antiplatelet has been demonstrated to be effective in the patients with high risk of TIA or
minor ischemic stroke (NIHSS<4). But there is still stroke progression although dual
antiplatelet. The ischemic stroke patients with NIHSS > 3 has been recommended to give
aspirin in most guidelines. Of those patients, mild to moderate stroke patients (3Phase:
Phase 4