Arresting Vertical Transmission of Hepatitis B Virus

• Status: Completed
• Trial end date: 2020-08-15
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this pilot study is to demonstrate the feasibility of adding HBV screening and treatment of pregnant women to the existing HIV PMTCT platform in order to prevent mother-to-child transmission of hepatitis B virus.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University of North Carolina, Chapel Hill
• Collaborators: Kinshasa School of Public Health; Ohio State University
• Treatments: Tenofovir; Vaccines

Criteria

Inclusion criteria:

• Pregnant women receiving care at Binza and Kingasani maternity centers presenting prior to 24 weeks gestation

• Infants born to HBV-positive women

Exclusion criteria:

• Participants who are severely sick and who require prolonged hospitalization.

• Any women who do not intend to stay in Kinshasa for prenatal care through delivery