Overview

Artemether/Lumefantrine and Nevirapine Interaction Study in HIV-infected Adults

Status:
Completed
Trial end date:
2009-12-01
Target enrollment:
Participant gender:
Summary
Despite the clinical significance of potential interactions between antimalarials and antiretrovirals, no drug interaction studies have been published and there is an urgent need to address this gap in current knowledge. This study aims to assess the drug interaction between the antimalarial Artemether/Lumefantrine used for management of uncomplicated malaria and Nevirapine-based antiretroviral therapy.
Phase:
Phase 4
Details
Lead Sponsor:
University of Cape Town
Collaborator:
London School of Hygiene and Tropical Medicine
Treatments:
Artemether
Artemether-lumefantrine combination
Artemether, Lumefantrine Drug Combination
Artemisinins
Lumefantrine
Nevirapine