Assessing the Effects of Tretinoin Cream on Human Skin With Optical Imaging Technologies

• Status: Completed
• Trial end date: 2016-12-01
• Target enrollment: 0
• Participant gender: Female

Summary

The researchers will assess the effects of treatment with tretinoin cream on human skin by using non-invasive optical imaging technologies.

• Phase: Early Phase 1
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: University of California, Irvine
• Collaborators: Beckman Laser Institute University of California Irvine; Unilever R&D
• Treatments: Tretinoin

Criteria

Inclusion Criteria:

• Female 45 years of age or older - Skin type scale I to III

Exclusion Criteria:

• Large amount of dark, coarse hair on the arms

• History of allergies to alpha hydroxy acids (AHAs), retinoids, soaps, fragrances, sunscreens or Latex

• Currently using over-the-counter AHA or retinol within one month or prescription retinoid within three months of the start of the study.

• History of skin cancer, including squamous or basal cell carcinoma at the treatment site or history of malignant melanoma.

• History of diabetes

• Currently pregnant or nursing