Assessing the Endometrial Environment in Recurrent Pregnancy Loss and Unexplained Infertility
Status:
Recruiting
Trial end date:
2026-07-01
Target enrollment:
Participant gender:
Summary
The purpose of this study is to determine if patients with recurrent pregnancy loss or
unexplained infertility have an altered uterine gene expression or uterine microbiome
(micro-organism composition) during the window of embryo implantation. Furthermore we would
like to assess for women with an abnormal uterine gene expression whether vaginal
progesterone medication improves or alters gene expression and for women with an abnormal
microbiome whether antibiotic treatment followed by probiotic treatment normalizes the
microbiome.
Phase:
Phase 2
Details
Lead Sponsor:
Stanford University
Collaborator:
Instituto Valenciano de Infertilidad, IVI VALENCIA