Assessing the Impact of Contraceptives on Bone Health Using 41Ca
Status:
Active, not recruiting
Trial end date:
2022-12-01
Target enrollment:
Participant gender:
Summary
This preclinical randomized crossover study will examine the effects of oral versus non-oral
contraceptive therapy on bone turnover in young exercising women. In an effort to expose the
route-dependent effects of oral versus non-oral contraceptive therapy on bone turnover, the
investigators will examine 1) the effects of ethinyl estradiol on bone calcium balance using
the 41Ca technology and 2) the underlying physiological mechanisms associated with the
effects of oral versus non-oral contraceptive therapy on net bone calcium balance.