Assessment of Combined Bowel Preparation for Capsule Endoscopy Study

• Status: Completed
• Trial end date: 2013-11-01
• Target enrollment: 0
• Participant gender: All

Summary

The investigators are conducting a study to see if taking a bowel preparation before having a capsule endoscopy is more helpful than the standard preparation of not eating after 7 PM the night before a capsule endoscopy in making it easier to see the small bowel in order to find the source of gastrointestinal bleeding.

• Phase: Phase 1
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Mayo Clinic
• Treatments: Metoclopramide; Simethicone

Criteria

Inclusion Criteria:

1. Age > 18 years old

2. Gastrointestinal bleeding as indication for capsule endoscopy.

3. Ability to give informed consent

Exclusion Criteria:

1. Subject has an allergy to polyethylene glycol or other adverse reaction to a previous bowel preparation with PEG3350 (MoviPrep®), metoclopramide, or simethicone;

2. Subjects has gastrointestinal motility disorder;

3. Subjects had stomach or small bowel resection;

4. Pregnancy;

5. Subjects has pheochromocytoma;

6. Subjects has uncontrolled hypertension;

7. Subjects has seizure disorders;

8. Subjects has concurrent MAO inhibitor use;

9. Subject has G6PD deficiency;

10. Subjects has swallowing disorder (including impaired gag reflex);

11. Subjects has hyponatremia with serum sodium less than 130 mm0l/L