Assessment of Inhibition of Biofilm Formation and Plaque Bacterial Count of Fluoride Varnish Containing Chlorhexidine and Cetylpyridinium Chloride Versus Conventional Fluoride Varnish

• Status: Recruiting
• Trial end date: 2020-08-01
• Target enrollment: 0
• Participant gender: All

Summary

Two different Fluoride varnish systems(Fluoride varnish containing Chlorhexidine and Cetylpyridinium Chloride (CPC) and conventional fluoride) will be applied to high caries risk patients to assess their clinical effects on plaque accumulation and plaque bacterial count .

• Phase: Phase 4
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Cairo University
• Treatments: Cetylpyridinium; Chlorhexidine; Chlorhexidine gluconate; Chlorhexidine, thymol drug combination; Fluorides; Fluorides, Topical

Criteria

Inclusion Criteria:

Patients with good general state of health.

• No signs of periodontitis.

• Patients had a recorded high bacterial count after caries risk assessment.

• No antibiotic treatment within 1 month prior to the start of the trial.

• No current medication with anti-inflammatory drugs.

• No use of antiseptic mouth rinses.

• Non-smokers.

Exclusion Criteria:

• Patients with disabilities, systemic disease or severe medical conditions.

• Patients with severe or active periodontal disease.

• Antibiotic treatment within 1 month prior to the start of the trial.

• Current medication with anti-inflammatory drugs.