Assessment of Intranasal Glucagon on Endogenous Glucose Production
Status:
Completed
Trial end date:
2016-03-01
Target enrollment:
Participant gender:
Summary
Peripheral glucagon action increases hepatic glucose production. In rodents hypothalamic
action of glucagon paradoxically suppresses glucose production. Intranasally administered
peptides have been shown to preferentially enter the central nervous system. We assessed the
effects of intranasal glucagon on hepatic glucose production