Overview

Assessment of Molecular Remission by ASO-qPCR After Bortezomib-dexamethasone (Vel/Dex) Followed by ASCT

Status:
Completed
Trial end date:
2015-07-01
Target enrollment:
Participant gender:
Summary
The primary objective of this study is to determine the rate of molecular remissions (MolR) assessed by ASO-RQ-PCR technique after induction treatment with bortezomib and dexamethasone (Vel/Dex) prior to high-dose therapy with melphalan and autologous stem cell transplantation (HDT-ASCT), and after HDT-ASCT in patients with multiple myeloma.
Phase:
Phase 2/Phase 3
Details
Lead Sponsor:
Tampere University Hospital
Collaborators:
Central Hospital of Kanta-Hame
Helsinki University Central Hospital
Janssen-Cilag Ltd.
Jyväskylä Central Hospital
Kanta-Häme Central Hospital
Kuopio University Hospital
Oulu University Hospital
Päijänne Tavastia Central Hospital
Seinajoki Central Hospital
Turku University Hospital
Treatments:
BB 1101
Bortezomib
Dexamethasone
Dexamethasone 21-phosphate
Dexamethasone acetate