Assessment of Two Levels of Arterial Pressure on Survival in Patients With Septic Shock

• Status: Completed
• Trial end date: 2012-09-01
• Target enrollment: 0
• Participant gender: All

Summary

The ideal mean arterial pressure in patients with septic shock is unknown. The expert's recommandations have stated a target between 65 and 70 mm Hg. However the scientific basis are weak. Indead there are only few prospective studies which addressed this question without clear answer. Therefore we designed a RCT in order to assess the effect on mortality of two levels of mean arterial pressure in patients with septic shock.(800 patients, 30 centres)

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University Hospital, Angers
• Treatments: Benzocaine

Criteria

Inclusion Criteria:

• patients with septic shock according criteria of Bone

• minimal dose of norepinephrine

• Written informed consent obtained from the patient or surrogate

Exclusion Criteria:

• Age < 18 years

• Pregnancy

• Participation in other trials with the same endpoints

• moribund

• absence of registration in french health care system

• patient protected by law