Association Between Fluid Administration, Oxytocin Administration, and Fetal Heart Rate Changes

• Status: Recruiting
• Trial end date: 2022-04-01
• Target enrollment: 0
• Participant gender: Female

Summary

Fetal heart rate patterns are an important parameter in the diagnosis of non-reassuring fetal status. Combined-spinal epidural analgesia is a method of initiating labor analgesia used by approximately 90% of the parturients at Prentice Women's Hospital. Optimizing the variables which could affect fetal heart rate patterns at the time of initiation of analgesia, such as fluid administration and oxytocin management, could help us provide better care for our patients and their fetuses.

Hypotheses: Patients who receive a 1000 mL fluid bolus and lower rates of oxytocin administration will have fewer non-reassuring fetal heart rate (FHR) changes.

• Phase: N/A
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Northwestern University
• Treatments: Oxytocin

Criteria

Inclusion Criteria:

• Age 18 and over

• Healthy nulliparous or multiparous women

• Term (>36 week gestation)

• Singleton pregnancy

• Spontaneous labor or spontaneous rupture of membranes

• Receive oxytocin

• Request neuraxial analgesia

Exclusion Criteria:

• Under 18 years old

• Presence of any systemic disease (ex: diabetes mellitus, hypertension, preeclampsia

• Use of chronic analgesic medications

• Prior administration of system opioid labor analgesia

• Non-vertex presentation

• Induction of Labor

• Contraindication to neuraxial analgesia