Association of Different Doses of Clonidine in Caudal Epidural Anesthesia for Hypospadias Surgery

• Status: Completed
• Trial end date: 2015-11-01
• Target enrollment: 0
• Participant gender: Male

Summary

The use of increasing doses of clonidine ssociated to bupivacaine in caudal epidural block provides better postoperative analgesia compared whit analgesia provide by bupivacaine alone

It is a randomized, double blind study, involving 80 children with ages from 1 to 10 years old, following eletive hypospadias surgery, under general anesthesia and caudal epidural block . The patients will be divided into 4 groups: bupivacaine alone, bupivacaine plus clonidine 1mcg/kg, bupivacaine plus clonidine 2 mcg/kg, bupivacaine plus clonidine 3 mg/kg. The peroperative consumption of anesthetics gases, heart rate and arterial blood pressure will be recorded. Postoperative pain will be evaluated by using FLACC scale ( faces , legs, activity , cry , consolability ) . Requiriments for supplementary postoperative analgesia at 24 h will be avaiable.

• Phase: Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Federal University of Minas Gerais
• Treatments: Anesthetics; Bupivacaine; Clonidine; Diazepam

Criteria

Inclusion Criteria:

• CHildren 1 - 10 years old.

• ASA I E II ( American Society of Anesthesiology)

• hypospadias surgery

Exclusion Criteria:

• parents refuse

• Infection

• Coagulation disorders

• Allergy to anesthetics

• Abnormalities of the sacral spine