Association of Polymorphisms in the Androgen Receptor Gene and Finasteride Response in Women With Androgenetic Alopecia

• Status: Completed
• Trial end date: 2009-12-01
• Target enrollment: 0
• Participant gender: Female

Summary

Previous studies of finasteride treatment in women with hair loss have failed to show positive results, yet, some women have responded anecdotally. Given that polymorphisms of the androgen receptor gene which confer androgen sensitivity impact male response to finasteride therapy, it was hypothesized that the same polymorphism in women may identify the group that will respond. This study is designed to test the impact of finasteride therapy on hair loss in postmenopausal women.

• Phase: Phase 1
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: HairDx, LLC
• Treatments: Androgens; Ascorbic Acid; Estrogens, Conjugated (USP); Finasteride; Methyltestosterone

Criteria

Inclusion Criteria:

• women with hair loss

Exclusion Criteria:

• pre menopausal,

• metabolic or medication or non-androgenetic causes of hair loss,

• diffuse hair loss