Atorvastatin Effect on Contrast Induced Nephropathy in Diabetic Patients Undergoing Elective Coronary Intervention

• Status: Completed
• Trial end date: 2020-05-05
• Target enrollment: 0
• Participant gender: All

Summary

Investigate of the potential benefit of acute pretreatment with high dose atorvastatin (80 mg) in reduction of the incidence of CIN in diabetic patients indicated for elective coronary intervention.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Mohamed Abdelfatah
• Treatments: Atorvastatin

Criteria

Inclusion Criteria:

• 200 diabetic patients with indication for coronary intervention participated in the study

Exclusion Criteria:

1. Current statin treatment within the previous three months.

2. Chronic renal failure patients on renal dialysis, or serum creatinine more than 1.5 mg/dl.

3. Severe co-morbidities i.e. patients with cancer, advanced liver cirrhosis.

4. Contraindications to statin therapy.

5. Contrast media injection within the preceding 10 days.

6. Pregnancy.

7. Refusal of consent.