Atorvastatin for Prevention of Postoperative Atrial Fibrillation After Off-Pump Coronary Artery Bypass Grafting Surgery

• Status: Completed
• Trial end date: 2007-05-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to determine whether pretreatment with atorvastatin protects against atrial fibrillation following off-pump coronary artery bypass graft surgery.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Samsung Medical Center
• Treatments: Atorvastatin; Atorvastatin Calcium

Criteria

Inclusion Criteria:

• consecutive patients scheduled for the elective off-pump CABG surgery

Exclusion Criteria:

• prior statin use

• previous episodes of atrial fibrillation

• impaired renal function with serum creatinine >2mg/dL

• serum aspartate aminotransferase or alanine aminotransferase concentrations more than 3 times the upper limit of normal

• a malignancy or inflammatory disease