Atrial Fibrillation Without Hemodynamic Instability in the Intensive Care Unit
Status:
Completed
Trial end date:
2009-12-01
Target enrollment:
Participant gender:
Summary
Atrial fibrillation (AF) is an abnormal heart rhythm that is common among patients who are
admitted to an intensive care unit (ICU) of a hospital. It is usually a transient occurrence
that resolves as the patient recovers from their underlying condition. However, patients who
develop AF can present with a very rapid heart rate that in some cases can put stress on the
heart which can lead to life threatening heart attacks, low blood pressure or breathing
problems. Not all patients with AF will have unstable heart function but those who have rapid
heart rates can worsen quickly. The goals of treatment for AF with a rapid heart rate but no
unstable heart function are two fold. Patients can be treated by controlling the heart rate
and/or by attempting to convert the AF to a normal heart rhythm. The heart rate can be
controlled by medication and the AF can be converted by either electrical cardioversion (an
electric shock that jump-starts the heart) or medication. Currently it is unknown if the goal
of treatment should be to simply control the heart rate and wait for the patient to
spontaneously convert to a normal heart rhythm or convert the AF with medication for patients
who only have the rapid heart rate.
The objective of this project is to conduct a pilot study to determine if it would be
feasible to conduct a larger definitive trial that would answer the following question:
Should the goal of treatment be to control the rapid heart rate or resolve the abnormal heart
rhythm in patients with AF who have a rapid heart rate without unstable heart function.