Atropine Versus no Atropine for Neonatal Rapid Sequence Intubation

• Status: Unknown status
• Trial end date: 2014-06-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to compare heart rate in infants who receive atropine as a part of their medication before intubation to those who do not.

To be able to find out , we need to divided babies into 2 groups;

group 1 : receives atropine + sedation + muscle relaxant group 2 : receives water or saline ( placebo group) + sedation + muscle relaxant

Then we need to compare heart rate during intubation and duration of intubation between the 2 groups.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University of Manitoba
• Treatments: Atropine; Fentanyl; Succinylcholine

Criteria

Inclusion Criteria:

• Any infant (preterm and term) up to 46 weeks corrected age requiring (nonemergent) intubation.

• IV access is obtained

• Informed parental consent

Exclusion Criteria:

• Emergent intubation or need for resuscitation

• Congenital cyanotic heart disease

• Obvious airway abnormalities

• History of myopathy or family history of malignant hyperthermia or known history of phosphocholinesterase deficiency