Overview

Atrovent in Exercise Induced Laryngeal Obstruction (EILO)

Status:
Completed
Trial end date:
2020-10-31
Target enrollment:
Participant gender:
Summary
Exercise Induced Laryngeal Obstruction (EILO) is a condition not uncommon in otherwise healthy young people. EILO is caused by posteromedial collapse of supraglottic structures or medialization of the vocal folds, or both, during high intensity exercise. There are currently no treatments available that is properly evidence based. However, case reports suggest a possible effect from the "asthma drug" Ipratropium Bromide (Atrovent®). The current project is an open label pilot study, aiming to test if Atrovent can influence the occurence of EILO, either postponing the onset during exercise or fully prevent the condition to occur.
Phase:
Phase 1/Phase 2
Details
Lead Sponsor:
Haukeland University Hospital
Treatments:
Bromides
Ipratropium