Augmenting Atropine Treatment for Amblyopia in Children 3 to < 8 Years Old
Status:
Completed
Trial end date:
2013-11-01
Target enrollment:
Participant gender:
Summary
This study is designed to evaluate the effectiveness of adding a plano lens to weekend
atropine after visual acuity has stabilized with weekend atropine but amblyopia is still
present. Children ages 3 to <8 years with visual acuity of 20/50 to 20/400 in the amblyopic
eye will be enrolled in a run-in phase with weekend atropine until no improvement, followed
by randomization of eligible patients to weekend atropine treatment with a plano lens over
the sound eye versus without a plano lens over the sound eye. The primary objective is to
determine if adding a plano lens to weekend atropine will improve visual acuity in patients
with amblyopia still present after visual acuity has stabilized with initial treatment.