Auricular Concha Electro-acupuncture for the Treatment of Depression

• Status: Unknown status
• Trial end date: 2019-08-01
• Target enrollment: 0
• Participant gender: All

Summary

The objective of this study was to compare the therapeutic effects of Auricular Concha Electro-acupuncture and Citalopram on patients with major depressive disorder (MDD).

• Phase: Early Phase 1
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: China Academy of Chinese Medical Sciences
• Treatments: Citalopram; Dexetimide

Criteria

Inclusion Criteria:

1. The diagnosis is consistent with DSM-V diagnostic criteria for mild-to- moderate depression;

2. Patients with the first onset or recurrence of the disease have not been treated with antidepressant or without antidepressant treatment before treatment for 3 months;

3. Age from 18 to 65 years old, with no gender;

4. Outpatient;

5. 17 Item Hamilton Depression Rating Scale (HAMD-17) score > 7, and <24;

6. Signed informed consent.

Exclusion Criteria:

1. In addition to depression, it conforms to the diagnostic criteria of any psychiatric disease;

2. Patients with a history of schizophrenia or other mental illness;

3. Patients with cognitive impairment or personality disorder;

4. In the past 6 months, patients who have met the DSM-V criteria for substance related and addictive disorders;

5. Before entering the group, any other antidepressant treatment is being accepted;

6. Patients with serious body disease, such as heart disease (namely Ⅱ and Ⅱ above cardiac function) , obvious abnormalities of liver and kidney function (Biomarkers more than 3 times normal);

7. Serious suicidal ideation or suicidal behavior.