Adjuvant use of fibrin glue in the fistula tract may promote healing in low-output
enterocutaneous fistulas. However, there are only few studies that report autologous glue
application in a larger patient group or clinical-controlled studies in this setting. The aim
of this study was to investigate the efficacy and safety of autologous platelet-rich fibrin
glue (PRFG) in the treatment of low-output digestive fistulas and compare them with
conservative management without the use of adjuvant application of FG into the fistulous
tract.