Autologous Stem Cell Transplantation in Patients With Systemic Sclerosis
Status:
Recruiting
Trial end date:
2025-08-01
Target enrollment:
Participant gender:
Summary
The purpose of this study is to determine whether a regimen of high-dose immunoablative
therapy will demonstrate safety that is consistent or improved with other published regimens
in SSc patients, while maintaining a treatment effect. We also hypothesize that our
mechanistic studies will yield biomarkers that may herald disease recurrence or progression
following alterations in the recovery of immune cells in the skin and/or bronchial lavage or
blood.