Overview

Avelumab With Bempegaldesleukin With or Without Talazoparib or Enzalutamide in Advanced or Metastatic Solid Tumors

Status:
Terminated
Trial end date:
2020-09-29
Target enrollment:
Participant gender:
Summary
Evaluation of the combination of avelumab + bempegaldesleukin (NKTR-214 ) in locally advanced squamous cell carcinoma of the head and neck ( metastatic SCCHN) and avelumab + bempegaldesleukin (NKTR-214) + talazoparib or enzalutamide in metastatic castration resistant prostate cancer (mCRPC).
Phase:
Phase 1/Phase 2
Details
Lead Sponsor:
Pfizer
Collaborators:
Astellas Pharma Inc
EMD Serono
Nektar Therapeutics
Treatments:
Antibodies, Monoclonal
Avelumab
Talazoparib