Azacitidine and Entinostat in Treating Patients With Metastatic Colorectal Cancer
Status:
Completed
Trial end date:
2014-05-01
Target enrollment:
Participant gender:
Summary
This phase II trial is studying how well giving azacitidine together with entinostat works in
treating patients with metastatic colorectal cancer. Drugs used in chemotherapy, such as
azacitidine, work in different ways to stop the growth of tumor cells, either by killing the
cells or by stopping them from dividing. Entinostat may stop the growth of tumor cells by
blocking some of the enzymes needed for cell growth. Giving azacitidine together with
entinostat may kill more tumor cells.