Azathioprine Based on Endoscopy After Clinical Remission in Moderate to Severe Ulcerative Colitis

• Status: Terminated
• Trial end date: 2018-12-01
• Target enrollment: 0
• Participant gender: All

Summary

The aim of this study is to determine whether azathioprine is effective for mucosal healing in UC patients who achieved clinical remission by the first course of corticosteroids but not mucosal healing in endoscopy.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Kyungpook National University; Kyungpook National University Hospital
• Collaborator: Celltrion
• Treatments: Azathioprine

Criteria

Inclusion Criteria:

• Ulcerative colitis patients with moderate to severe activity who achieved a clinical remission by the first course of corticosteroids

• Newly diagnosed or without steroid use during last 1 year

• Endoscopic Mayo subscore >0

Exclusion Criteria:

• Patients with azathioprine or biologics therapy