Overview

BI-754091 and Afatinib for Refractory Esophageal Squamous Cell Carcinoma (BEAR Study)

Status:
Enrolling by invitation
Trial end date:
2023-05-01
Target enrollment:
Participant gender:
Summary
This is an open-label, single arm, multi-center study, assessing efficacy and safety of BI-754091 in combination with afatinib as treatment in patients with advanced or metastatic ESCC refractory to at least 1 line of systemic treatment (including chemotherapy or radiation therapy).
Phase:
Phase 2
Details
Lead Sponsor:
National Health Research Institutes, Taiwan
Collaborators:
Chang Gung Memorial Hospital
China Medical University Hospital
Kaohsiung Medical University Chung-Ho Memorial Hospital
National Cheng-Kung University Hospital
Taipei Veterans General Hospital, Taiwan
Treatments:
Afatinib