BPO vs Hibiclens Soap for Surgical Preparation

• Status: Unknown status
• Trial end date: 2019-09-01
• Target enrollment: 0
• Participant gender: Male

Summary

This is a randomized trial of benzoyl peroxide soap versus Hibiclens soap for surgical preparation. The objective is to determine whether benzoyl peroxide soap, commonly available in drug stores for over-the-counter acne treatment, is as or more effective than the standard surgical preoperative soap, Hibiclens soap (chlorhexidine gluconate), in reducing loads of Propionibacteria (Propi) on or under the skin of patients prior to shoulder arthroplasty (joint replacement).

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University of Washington
• Treatments: Benzoyl Peroxide; Chlorhexidine; Chlorhexidine gluconate

Criteria

Inclusion Criteria:

• Male subjects

• Subjects scheduled for elective shoulder arthroplasty at the University of Washington Medical Center

• Subjects between ages 18-89

Exclusion Criteria:

• Subjects who self-report very sensitive skin

• Subjects who are sensitive to benzoyl peroxide

• Subjects who are allergic to chlorhexidine

• Subjects who had recent prior use of antibiotics (or expect to use them prior to surgery)

• Subjects who had recent use of acne treatment

• Subjects who are not fluent in English.