Overview

BRAZAN Trial in Frontline MCL

Status:
NOT_YET_RECRUITING
Trial end date:
2039-11-01
Target enrollment:
Participant gender:
Summary
This study aims to evaluate the efficacy and safety of an induction regimen combining Bendamustine, Rituximab, Cytarabine (AraC), and Zanubrutinib (BRAZAN), followed by maintenance therapy with Zanubrutinib and Rituximab with or without Sonrotoclax in participants with Mantle Cell Lymphoma (MCL). The names of the study drugs involved in this study are: * bendamustine (a type of alkylating agent) * rituximab (a type of monoclonal antibody) * cytarabine (a type of antineoplastic) * zanubrutinib (a type of kinase inhibitor) * sonrotoclax (a type of BCL2 inhibitor)
Phase:
PHASE2
Details
Lead Sponsor:
Christine Ryan
Collaborator:
BeiGene
Treatments:
Bendamustine Hydrochloride
Cytarabine
Rituximab
zanubrutinib