Baclofen in the Treatment of Muscle Cramps in Patients With Cirrhosis

• Status: Unknown status
• Trial end date: 2014-11-01
• Target enrollment: 0
• Participant gender: All

Summary

Patients with cirrhosis often experience muscle cramps with varying severity. The mechanism of their occurrence is not yet understood. Muscle cramps in patients with cirrhosis are associated with significantly diminished quality of life.

The aim of the study is to assess the efficacy of baclofen in the treatment of muscle cramps in patients with liver cirrhosis.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Tanta University
• Treatments: Baclofen; gamma-Aminobutyric Acid

Criteria

Inclusion Criteria:

• Cirrhosis

• Muscle cramps( ≥3 cramps per week )

Exclusion Criteria:

• Allergy to baclofen

• Renal impairment

• Pregnant and lactating women

• Peripheral vascular disease

• Peripheral neuropathy

• Medications as calcium channel blockers, conjugated estrogens and naproxen.