Overview

Bacterial Decolonization Plus Intraoperative Angiography for Soft Tissue Sarcomas Receiving Preoperative Radiotherapy (CONCERTO)

Status:
NOT_YET_RECRUITING

Trial end date:
2027-10-31

Target enrollment:

Participant gender:

Summary

This trial will investigate the combination of two low-cost, non-toxic strategies to assess whether they can reduce the risk of acute major wound complications in soft tissue sarcoma of the lower extremity. Intranasal mupirocin ointment twice daily and chlorhexidine body cleanser once daily for 5 days prior to radiation therapy and repeated for 5 days every 2 weeks during radiation therapy may significantly reduce the risk of acute radiation dermatitis. That, along with use of indocyanine green (ICG) angiography at the time of wound closure.

Phase:

PHASE2

Details

Lead Sponsor:

Adam Olson

Collaborator:

Pittsburgh Cure Sarcoma

Treatments:

chlorhexidine gluconate