B&O for TLH Post-operative Pain and Nausea

• Status: Completed
• Trial end date: 2017-05-31
• Target enrollment: 0
• Participant gender: Female

Summary

A prospective, single-center, double-blind, randomized, placebo-controlled trial to assess the impact of immediate post-operative placement of a Belladonna and Opium (B&O) rectal suppository on postoperative pain and nausea following laparoscopic and robot-assisted hysterectomy.

• Phase: Phase 4
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Anna Reinert
• Collaborators: University of Maryland; University of Maryland, College Park
• Treatments: Glycerol; Opium

Criteria

Inclusion Criteria:

• between ages 18 and 75,

• undergoing level I total laparoscopic or robot-assisted hysterectomy with or without bilateral salpingo-oophorectomy, cystoscopy, lysis of adhesions, or surgical treatment of endometriosis

Exclusion Criteria:

• contraindications to the use of B&O (i.e. glaucoma, severe hepatic or renal disease, bronchial asthma, history of narcotic idiosyncracies, respiratory depression, convulsive disorders, acute alcoholism or delirium tremens, or regular use of an anticholinergic medication (twice per week or more frequently)

• additional surgical procedures being performed